Mr G’s MND Fun Run 2016

Mr G’s MND Fun Run 2016 was another huge success and a fantastic day!  Thanks to all the runners, supporters and volunteers. And of course a massive thank you to Donald, Brynja and their families!

For more info and pictures of the day go to:  http://www.facebook.com/MrGsMND5kmFunRun/

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Mr G’s MND 5KM Fun Run – 4th September 2016

We are very excited about the upcoming fun run being organised by the amazing (and award winning) Brynja Duthie in honour of Donald Grewar. Also very humbled to have the proceeds of the fun run supporting our research into MND.

For more info go to: http://www.facebook.com/MrGsMND5kmFunRun/

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Postdoc position available

We are currently looking for an enthusiastic and motivated Postdoctoral Researcher with a proven track record in neuroscience research to work on a project investigating the role of dysfunctional crosstalk between astrocytes and motoneurons in the devastating neurodegenerative disease Amyotrophic Lateral Sclerosis (ALS).

For informal enquiries please contact Dr Gareth Miles (gbm4@st-andrews.ac.uk).

For more information and to make a formal application please follow the link below.

View the vacancy online

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Paper on organic LEDs for high-resolution optogenetics published in Science Advances

Our collaborative work with colleagues from Physics, Malte Gather and Anje Steude, has just been published in Science Advances.

A. Steude, E.C. Witts, G.B. Miles, M.C. Gather (2016). Arrays of microscopic organic LEDs for high-resolution optogenetics. Science Advances, 2(5). [Link]

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Gareth receives International Paulo Gontijo Award in Medicine

Very honoured and humbled to be presented the 7th International Medicine PG Award at the ALS/MND Symposium in Orlando last Decemeber – Gareth.

Instituto Paulo Gontijo

Research@StAndrews blog

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New PhD project: Investigating the role of sodium pumps in motor control

The NCM lab is seeking applicants for a PhD project investigating the role of sodium pumps in spinal motor control.

For more information follow this link

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Adenosine-mediated modulation of spinal neurons – paper accepted for publication

Emily and Filipe’s study of the effects of adenosine receptor activation on ventral horn interneurons and motoneurons has just been accepted for publication in the Journal of Neurophysiology.

Emily C. Witts, Filipe Nascimento and Gareth B. Miles. “Adenosine-mediated modulation of ventral horn interneurons and spinal motoneurons in neonatal mice.” Journal of Neurophysiology (in press).

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Glial-neuronal interactions paper accepted for publciation

David’s study of glial-neuronal interactions within spinal motor control circuitry has just been accepted for publication in PLOS ONE.

David Acton and Gareth B. Miles. “Stimulation of glia reveals modulation of mammalian spinal motor networks by adenosine” PLOS ONE (in press).

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Post doc position available

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The Neural Control of Movement (NCM) Lab at the University of St Andrews is currently looking for an enthusiastic and motivated post doctoral researcher to work on a project investigating the role of glial cells in spinal motor control circuitry. This project will utilise a combination of cutting edge molecular genetic, electrophysiological, calcium imaging and optogenetic techniques applied to in vitro rodent spinal cord preparations and human induced pluripotent stem cell-derived models. The project will be conducted in collaboration with Dr Stefan Pulver (St Andrews) and Prof Siddharthan Chandran (Edinburgh).

The NCM lab, headed by Dr Gareth Miles, is part of a world class motor control research cluster at St Andrews and a wider Institute of Behavioral and Neural Sciences (IBANS) consisting of more than 60 primary investigators from 5 different Schools. Founded in 1413, the University St Andrews is situated in a picturesque medieval town on the east coast of Scotland between Edinburgh and Dundee.

For informal enquiries please contact Dr Gareth Miles (gbm4@st-andrews.ac.uk).

Click for PDF copy of Postdoc advertisement

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Human iPSC-based ALS study accepted for publication

Anna-Claire’s study of ALS pathophysiology utilising human iPSCs has just been accepted for publication in Nature Communications. 

Anna-Claire Devlin, Karen Burr, Shyamanga Borooah, Joshua D. Foster, Elaine M. Cleary, Imbisaat Geti, Ludovic Vallier, Christopher E. Shaw, Siddharthan Chandran and Gareth B. Miles. “Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability.” Nature Communications (in press).

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